Hematology

Overview of Hematology

Hematology encompasses the medical field dedicated to investigating the origins, prognosis, management, and prevention of blood-related disorders. It focuses on addressing conditions impacting blood production and its constituents. Hematological research frequently intersects with oncology, sharing common therapeutic approaches. Disorders such as blood cancers (e.g., leukemia, myeloma, lymphoma), bleeding disorders (e.g., hemophilia), and clotting abnormalities are among the myriad conditions studied within hematology.

BsAbs in Hematology

Immunotherapy offers a promising avenue for enhancing outcomes in patients with recurrent or refractory hematological malignancies by circumventing the cytotoxic mechanisms of conventional treatments. One compelling approach within immunotherapy involves redirecting T cells to target hematological cancers using bispecific antibodies (BsAbs). BsAbs present an attractive alternative to adoptive T-cell therapies. For instance, BsAbs targeting CD19 on B-cell malignancies and CD3 on T cells have exhibited potent antitumor effects in both preclinical and clinical settings. These BsAbs are being extensively investigated for their efficacy in treating various hematological cancers, including B-cell lymphoblastic leukemia and lymphoma, acute myeloid leukemia, and multiple myeloma.

Creative Biolabs offers an extensive selection of over 100 BsAb options to bolster research in hematology therapy. Tailored customization options are accessible to cater to specific research requirements regarding hematology conditions. We are ready to assist your scientific and medical research initiatives.