Immunotherapy has become a new hope against cancer. CAR-T cell therapy is achieved by using genetic engineering method to express chimeric antigen receptors on T cells obtained from donner patients. These chimeric antigenRead More…
Comparison between CAR-T and TCR-T
As a matter of fact, tumor immunotherapy is divided into two categories. One is to show immune cells the tumor features, then direct them to locate and kill tumor cells. And anotherRead More…
A New Immunotherapy Called CAR-T Will Beat Cancer Surprisingly
CAR-T (Chimeric Antigen Receptor T-Cell), as an immunocytotherapy regimen, has attracted a lot of attention from academics, doctors, patients, and investors worldwide. What does make it so attractive and popular? CAR-T modifies humanRead More…
The First CAR-T Therapy Drug Is Approved and Recommended by FDA Experts Unanimously on a 10-0 Vote!
Novartis’ chimeric antigen receptor T cell therapy (CAR-T) was supported and approved unanimously (10-0) on July 12th by the U.S. FDA Advisory Committee experts. This vote marks the key milepost of thisRead More…
Will the First CAR-T Therapy Be Approved on July 12? —Novartis CTL019
On July 12, FDA experts will discuss whether CAR-T CTL019 can be on the market, which is an assessment of the CTL019 Biologics License Application (BLA) submitted by Novartis and will evaluate the dataRead More…
The Appearance of CAR-T
CAR-T (T cell chimeric antigen receptor), as an immune cell therapy has attracted worldwide attention including academics, doctors, patients, and investors. However, what’s CAR-T exactly? What’s the background of it? What’s the currentRead More…
The Exploration of CAR T Cells Validation
Chimeric antigen receptor (CAR) T cells have hit the cancer immunotherapy area in the past few years. ‘A CAR therapy for cancer, using a technique called adoptive cell transfer, has been approvedRead More…
The Development of CAR Gene Construction
CAR-T is chimeric antigen receptor T cell immunotherapy, which modifies T cell receptor by CAR and transforms it into the scFV segment in the binding domain of monoclonal antibodies. A classic CAR-TRead More…
The Introduction of T Cell Proliferation Assay
Cell proliferation is an important vital sign of the organism in a splitting manner. Single-celled organisms produce new individuals in the form of cell division, while a multicellular organism that produces newRead More…
TCR, A New Star of Immune Cell Therapy
Immune cell therapy, the fourth major cancer treatment following surgery, radiotherapy, and chemotherapy, has been recognized as the most active and promising treatment in the comprehensive tumor treatment in the 21st century.Read More…
