On September 2, 2024, Nature Materials published a study titled “Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery.” This research challenges traditional views by revealing that tumor-secreted exosomesRead More…
Extracellular vesicles (EVs) secreted by all cell types are involved in the intercellular communication, delivering regulatory factors that influence cell and tissue phenotypes in both normal and diseased tissues. Therefore, EVs representRead More…
Extracellular vesicle (EV)-based therapeutic approaches still pose challenges in clinical application due to their rapid clearance, limited residence, and low yield. Although hydrogels possess the ability to impede physiological clearance and increaseRead More…
Extracellular vesicles (EVs) are biological nanoparticles that mediate short- and long-distance intercellular communication, delivering bioactive payloads. Short-distance communication occurs in the interstitium, while long-distance communication necessitates transport through the blood circulation toRead More…
A recent review was published in Nature Reviews Rheumatology delves into the promising therapeutic applications of mesenchymal stromal cell extracellular vesicles (EVs) in rheumatic diseases. Rheumatic diseases comprise a diverse range ofRead More…
Non-alcoholic fatty liver disease (NAFLD) is strongly linked to various cancers, including liver, breast, prostate, pancreatic, and colorectal cancer, surpassing its association with obesity alone. Patients with fatty liver disease exhibit aRead More…
Intercellular communication stands as a pivotal characteristic in tumor progression and metastasis. Extracellular vesicles (EVs), generated by diverse cells including tumor cells, serve as indispensable agents in cell-to-cell communication. They wield influenceRead More…
Exosomes, derived from multivesicular bodies, exhibit a cup-shaped under electron microscopy, with diameters ranging from 50 to 150 nanometers. Loaded with various contents, including nucleic acids, proteins, lipids, enzymes and metabolites. TheseRead More…
Prostate cancer is one of the most malignant tumors in men and remains incurable due to its heterogeneous and progressive nature. Genetic and epigenetic changes play important roles in prostate cancer development.Read More…
Extracellular vesicles (EVs) are nanoscale, naturally derived vesicles that contain a variety of bioactive molecules reflecting their origin. These nanovesicles have a natural ability to cross the blood-brain barrier and exhibit excellentRead More…