Science Advances: The Structure of Antibody IgM Is Redefined

October 25, 2018Biological Knowledge, Newsantibody development, Antibody Discovery, antibody structurebiolabs

In a new study, researchers from the University of Tokyo in Japan revealed the structure of a immune protein called immunoglobulin M (IgM) by using computer image analysis and electron microscopy imaging.Read More…

Three Scientists from US and UK Shared the 2018 Nobel Prize in Chemistry

October 4, 2018NewsAntibody, nobel prize, phage displaybiolabs

On October 3rd, the 2018 Nobel Prize in Chemistry was awarded to the field of biochemistry, in which Frances H. Arnold of US won half in recognition of her directed evolution ofRead More…

Overview of Four Progresses in Antibody Fields

September 1, 2018Antibody Engineering Research, Newsbispecific antibodies, humanized antibodiesbiolabs

1.  DotBio announced the establishment of a next-generation immuno-oncology drug based on domain antibody DotBio, a new company focused on the development of new anti-tumor drugs for humanized antibodies, has officially announcedRead More…

Overview on Characteristics of Tumor Immunotherapy

July 4, 2018Drug Discovery Research, Immunotherapy Research, Newsimmunotherapy, immunotherapy drug, monoclonal drug, tumor therapybiolabs

Unlike the mechanism of action of traditional treatments, immunotherapy is uniquely characterized by its long-term response and survival in efficacy, unconventional delayed response and pseudo-progression in response mode, a new assessment endpointRead More…

Nat Commun: Artificial Intelligence Helps Find Gene Mutations That Cause Gastric Cancer

May 7, 2018Biological Knowledge, Drug Discovery Research, Newscancer research, genome researchbiolabs

In a groundbreaking study, researchers from the Genome Institute of Singapore (GIS) developed a new computer model of machine learning (an artificial intelligence model, AI) to accurately find tumor mutations. They alsoRead More…

What You Should Know about Antibody Monomer

March 30, 2018Antibody Engineering Research, Biological Knowledge, NewsAntibody Discovery, fab, monoclonal antibody, recombinant antibody, ScFv, Therapeutic Antibodybiolabs

Most proteins have a tendency to form polymers, which are accompanied by slow polymer formation when they are produced, stored, transported, and injected into a patient. There are two reasons for whyRead More…

Monoclonal Antibodies Crucial to Fighting Emerging Infectious Diseases

March 29, 2018Biological Knowledge, NewsAntibody, Antibody Discovery, monoclonal antibody, Therapeutic Antibodybiolabs

Monoclonal antibodies (mAbs) — preparations of a specific type of antibody designed to bind to a single target — have shown promise in the fight against cancer and autoimmune diseases. They alsoRead More…

Roche Reports 5 Deaths After Dosing of Hemlibra

March 29, 2018Antibody Engineering Research, Drug Discovery Research, Newsantibody development, Antibody Discovery, bispecific antibody, Therapeutic Antibodybiolabs

Model of Factor VIII. © 3d ribbon/surface model of the human factor VIII after PDB 3CDZ. Ref.: Ngo JC, Huang M, Roth DA, Furie BC, Furie B (April 2008). DOI:10.1016/j.str.2008.03.001. Roche’s USRead More…

New Model, New drugs, and A ‘Remarkable’ Response in Adrenal Cancer

March 29, 2018Drug Discovery Research, Immunotherapy Research, NewsAntibody Discovery, genetic targets, humanized mouse modelbiolabs

“Two new studies use new models to identify genetic targets and test promising treatments for adrenal cancer. One patient was treated with the immunotherapy pembrolizumab and now more than a year afterRead More…

Cancer Drug R&D and Market Trends from 2006 to 2017

March 29, 2018Drug Discovery Research, Newsantibody development, Antibody Discovery, CAR-T, Novartis, Therapeutic Antibodybiolabs

Great Achievements Have Been Made in Cancer Drug Listing In 2006-2017, a total of 89 oncology therapies (NTDs) were approved by the Center for Drug Evaluation and Research (CDER). The Biologics EvaluationRead More…