Neuronal Assays

Based on the unrivaled expertise and experiences in neuroscience research, Creative Biolabs has developed novel neuronal assay services for global clients to speed up the development of projects.

Biology of Neuronal Cell

As the basic functional unit of the nervous system, neurons are the information-processing cells, and can be classified into three types: sensory neurons, motor neurons and interneurons based on their function. The three well-known functions of neurons include participation in signal reception, signal integration, and signal communication. More and more studies have shown that neurons play many important roles in brain development and are closely related to the pathogenesis of neurological diseases.

Neuronal Assay Services at Creative Biolabs

Creative Biolabs has robustly developed in vitro and in vivo platforms to provide reproducible neuronal assays for our clients all over the world. We are dedicated to designing comprehensive research practices and handling high-quality studies to support your biopharmaceutical development pipeline. We can provide a range of assays for our clients.

Customized Neuron Cell Identification Analysis

In combination with our severalin vitro platforms, we provide customized neuron cell identification analysis services:

• Neuron cell marker detection
• Neurite detection and quantification
• Activation of microglia

Fig.1 Marker detection of neuronal cells. (Felfly, 2011)

Neuronal Activity Assay

Neuronal activity plays an important role in the formation and function of neuronal circuits, which include synapse development, learning and memory. Disorders of these processes can lead to neurodevelopmental, neurological and psychiatric disorders, such as epilepsy and schizophrenia. Based on the unrivaled expertise, Creative Biolabs has developed custom end-to-end neuronal activity assays for our clients all over the world. We are dedicated to designing comprehensive research practices and handling high-quality in vitro studies to speed up the client's projects.

Neurite Outgrowth Assay

Neurite outgrowth is a critical process of neurogenesis. During neurogenesis, neurons branch into dendrites and axons. This process is important for communication between neurons. Initiation and subsequent extension of neurites involve complex intracellular signaling. The study of neurite is of great significance for neuropathological disorders, nerve injury/regeneration, and neuropharmacology. To help customers with better and faster projects, Creative Biolabs is committed to providing custom neurite outgrowth assay services to reduce the overall project development timeline for our clients.

Scientists at Creative Biolabs are dedicated to bringing together years of valuable experience to help our clients shorten the project journey. For further details, please don't hesitate to contact us.

References

1. Felfly, H.; et al. Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2011, 301(3): R727-45.
2. Varkuti, B.H.; et al. Neuron-based high-content assay and screen for CNS active mitotherapeutics. Science advances. 2020, 1;6(2): eaaw8702.
3. Frimat, J.P.; et al. The network formation assay: a spatially standardized neurite outgrowth analytical display for neurotoxicity screening.Lab on a Chip. 2010, 10(6): 701-9.

For Research Use Only | Not For Clinical Use