Gene Expression Profiling

Gene expression profiling is a powerful tool that measures gene activities(expressions) at the given cell for a certain time frame, to process thousands of cells at the same time, and generate a global map of cellular function can be generated. Creative Biolabs provides gene expression profiling services at the DNA and RNA levels to identify new drug targets, allowing the researcher to obtain a molecular snapshot of the tumor microenvironment. For the target recognition purpose, this method can also compare cells that are administrated by specific treatments with those are not. This comparison can evaluate treatment-related phenotypic changes on the molecular basis, hence, selecting proper target cells for further drug discovery studies.

Creative Biolabs has extensive knowledge on gene expression profiling. Our team is comprised by experts from different fields, ranging from molecular biology, genetics and bioinformatics. With advanced knowledge including DNA microarrays, transcriptomics sequencing, digital PCR and real-time PCR, our team is able to provide customized profiling service for our clients. We also tailor the solution to your project by selecting and optimizing the most appropriate technology.

Microarray Analysis

RNA-seq Analysis

Platforms
  • Affymetrix - a pioneer in microarray technology
  • Agilent - an integrated, flexible, open approach
  • Illumina - a highly reproducible, multiplex efficient and cost-effective option
  • Next-generation sequencing (NGS)
  • Single cell sequencing
  • In situ sequencing of fixed tissue
Applications
  • Genome wide gene expression studies
  • Low to medium sample throughput
  • Pre-designed and custom arrays (including design) available
  • Alternative gene spliced transcripts
  • Post-transcriptional modifications
  • Mutations/SNPs and gene fusion
  • Total RNA, miRNA, tRNA, and ribosomal profiling
  • Determine exon/intron boundaries
Features
  • For human, mouse, rat and model organisms
  • Cover a wide range of organisms for standard 3' gene expression
  • Standard genome-wide expression analysis
  • Highly repeatable, efficient and cost effective
  • Help you design the array (if applicable)
  • For human, mouse, rat and model organisms
  • Validation genes expression resulting from microarray
  • Characterization of all major immune cell types
  • Detect tumor infiltrating immune cells

Analysis Pipeline

  • Array Data Extraction
  • Detectable Signal
  • Data Normalization
  • Quantile
  • Statistical Testing
  • P-value Calculation
  • RNA-seq Analysis
  • Test Enrichment calculation
  • Final Report

Highlights of Our Comprehensive Services

  • Reliable microarray technology
  • Experienced staff will assist you with your experimental design
  • Fast turnaround time
  • Complete bioinformatics analysis
  • Expert technical support to assist with data interpretation

Scientists in Creative Biolabs are happy to provide you with one-stop gene expression profiling services and advice on the most appropriate solution to meet your project needs.

For more details, please feel free to contact us or send us a query directly.

For lab research only, cannot be used for any clinical use.

Online Inquiry

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