PSCA Assay Portfolio Service

Therapeutic Applications of PSCA

The Prostate Stem Cell Antigen (PSCA) is a GPI-anchored cell surface protein that has emerged as a critical, yet complex, biomarker in oncology. While its overexpression in prostate, pancreatic, and bladder cancers often correlates with aggressive disease, it can act as a tumor suppressor in others, like gastric cancer. This dual role makes it a fascinating "Jekyll and Hyde" molecule for researchers.

What We Can Offer

Cell-Based Assays

We provide cell proliferation, migration, and invasion assays to evaluate your therapeutic candidates' impact on cancer growth and metastatic potential. We also conduct cytotoxicity assays to measure a drug's direct killing effect and cytokine release assays to analyze immune responses.

Protein & Expression Analysis

Our ELISA service measures soluble PSCA in biofluids. Flow cytometry provides single-cell resolution, while immunohistochemistry and immunofluorescence offer precise visualization of protein expression in tissue sections.

Genomic Studies

Our genomic services investigate PSCA's genetic regulation. We use quantitative real-time PCR to measure mRNA expression, Luciferase reporter assays to study promoter activity, and ChIP assays to identify protein-DNA interactions.

In Vivo Models

To bridge the gap between in vitro and clinical results, our animal experiments use validated xenograft and syngeneic models to assess the efficacy and safety of your candidates. We evaluate tumor growth, survival, and pharmacokinetics/pharmacodynamics.

Highlights

Integrated Assay Portfolio

Our service is not a collection of fragmented, individual tests. We offer a synergistic suite of pre-validated assays designed to provide consistent, reproducible, and correlative data across different experimental platforms.

Accelerated Research Timelines

Our standardized and quality-controlled assays eliminate the need for time-consuming in-house development and validation. This allows you to bypass months of preparatory work and significantly accelerate your research timelines.

Expert Scientific Consultation

With two decades of experience in oncology research, our dedicated team provides unparalleled scientific and technical support. We partner with you at every stage of your project, offering expert guidance and a collaborative approach.

Consistent and Reliable Data

Our unified platform is engineered to eliminate the common pitfalls of data inconsistency. This ensures you can make informed decisions with a high degree of confidence, trusting that your data is both accurate and reliable.

Experience the Creative Biolabs advantage - Get a quote today.

Customer Reviews

Validated assays saved us months
The pre-validated cell-based assays for internalization kinetics were a game-changer. We were able to screen our antibody candidates much faster than we had anticipated, and the data were highly reproducible, which is critical for our regulatory filings. - My P.

Excellent support and follow-up
The consultation after the data delivery was invaluable. We were able to discuss the nature of PSCA's expression that we observed in our samples, and the Creative Biolabs team provided expert guidance on how to interpret these seemingly contradictory results. - Sa M.

FAQs

What types of samples can I submit for the PSCA assay portfolio service?

We can process a variety of sample types, including fresh or frozen cell lines, FFPE tissue blocks, and biofluids such as serum or plasma. We recommend a preliminary discussion to ensure your sample types are compatible with the assays you choose.

How does this service compare to purchasing individual assay kits?

Our integrated service saves you significant time and resources by eliminating the need for in-house assay validation, optimization, and troubleshooting. Our portfolio provides consistent, pre-validated data that is directly comparable across different assay types.

What are the key advantages of using Creative Biolabs' service?

The main advantages are our integrated approach, which ensures data consistency and reliability, and our team's extensive scientific expertise. We act as a partner, providing valuable consultation and helping you make informed decisions.

Related Services

Oncology Biomarker Discovery

Our oncology biomarker discovery service can help you identify novel protein, gene, or metabolite markers that correlate with PSCA expression or disease progression, offering a more complete picture of the tumor microenvironment.

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Protein Purification Services

Our protein expression and purification services can produce recombinant PSCA protein and other related proteins with high purity and yield, ensuring the foundational materials for your project are of the highest quality.