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Category Archives: Immunotherapy Research

new models to identify genetic targets and test promising treatments in adrenal cancer.

New Model, New drugs, and A ‘Remarkable’ Response in Adrenal Cancer

March 29, 2018Drug Discovery Research, Immunotherapy Research, NewsAntibody Discovery, genetic targets, humanized mouse modelbiolabs

“Two new studies use new models to identify genetic targets and test promising treatments for adrenal cancer. One patient was treated with the immunotherapy pembrolizumab and now more than a year afterRead More…

CAR-T

Latest Research Results on CAR-T Therapy Reveal a Possible Reason of CAR-T Neurotoxicity

December 21, 2017Immunotherapy ResearchCAR-Tbiolabs

There is no doubt that this year marks the beginning of CAR-T therapy owing to the advent of two CAR-T therapies and the changes that these therapies have brought to the lives ofRead More…

Actemra/RoActemra® Is Approved by FDA for the Treatment of Cytokine Release Syndrome Caused by CAR-T Therapy

November 6, 2017Immunotherapy ResearchActemra/RoActemra®, CAR-T, CAR-T cell therapy, cytokine release syndromebiolabs

Actemra/RoActemra® is the first FDA approved drug for treatment of serious or fatal cytokine release syndrome (CRS) caused by CAR-T therapy; CAR-T cell therapy is an immunotherapy used to treat certain typesRead More…

30Oct/17

Chinese Scientists Discovered Strong Oncolytic Virus Synergist

October 30, 2017Immunotherapy Research, NewsCAR-T, ERAD pathway, M1, oncolytic virusbiolabs

On August 24th, a reporter was informed from Prof. Guangmei Yan research group at Zhongshan University that this group of researchers identified and gained oncolytic virus M1 synergist with accurate treatment ofRead More…

An autoimmune disease is a pathological condition resulting from an abnormal immune response to tissues that can exist in the body,

Car-T for Autoimmune Disease and Blastoma Therapy

September 11, 2017Immunotherapy ResearchAutoimmune Disease, Blastoma Therapy, CAR-Tbiolabs

Car-T for Autoimmune Disease An autoimmune disease is a pathological condition resulting from an abnormal immune response to tissues that can exist in the body, affecting up to 50 million Americans in termsRead More…

Carcinoma is a type of cancer that originates in epithelial cells

The Application of CAR-T in Disease Treatment

September 7, 2017Immunotherapy ResearchCAR-T, Carcinoma Therapy, Leukemia therapy, Lymphoma therapybiolabs

Chimeric antigen receptor (CAR) modified T cells (CAR-T) as a new field of adoptive immune cell therapy has become a hot spot in recent research. In 1989, Israeli scholar Gross et al.Read More…

03Sep/17

The Exploration of CAR T Cells Validation

September 3, 2017Immunotherapy ResearchCAR T cell validation, CAR-T, T -cells animal testbiolabs

Chimeric antigen receptor (CAR) T cells have hit the cancer immunotherapy area in the past few years. ‘A CAR therapy for cancer, using a technique called adoptive cell transfer, has been approvedRead More…

01Sep/17

Carl June Published His Latest Paper: The Results of CAR-T Therapy Human Trials on the Treatment of Solid Tumors Shows Two Hurdles Still Need to Be Overcome!

September 1, 2017Immunotherapy Research, NewsCAR-T, CAR-T transfusion, CART-EGFRvIII, CTL019biolabs

In this month, FDA oncologic Drugs Advisory Committee agreed to the approval of Novartis’s CAR-T CTL019 therapy on a vote of 10:0 for the treatment of relapsed or refractory children and youngRead More…

31Aug/17

Is Bio-distribution Study Necessary for CAR-T Therapy?

August 31, 2017Immunotherapy ResearchCAR-T, CAR-T cell biodistribution studybiolabs

Biological therapy includes a variety of models, such as immunotherapy, gene therapy, regulation of angiogenesis therapy, small molecule targeting drugs and stem cells and tissue engineering regenerative medicine. Among them, cancer immunotherapyRead More…

22Aug/17

The Development of CAR Gene Construction

August 22, 2017Immunotherapy ResearchCAR gene constructs, car t generation, car t structure, CAR-T, universal car tbiolabs

CAR-T is chimeric antigen receptor T cell immunotherapy, which modifies T cell receptor by CAR and transforms it into the scFV segment in the binding domain of monoclonal antibodies. A classic CAR-TRead More…

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