Effective and targeted drug delivery remains a significant challenge in modern medicine. Researchers are employing biochemical engineering approaches to repurpose extracellular vesicles (EVs) as drug delivery vehicles. Studies have demonstrated that displayingRead More…
Extracellular vesicles (EVs) have emerged as a promising avenue for advanced drug delivery. One effective strategy for loading these EVs with desired cargo involves genetically fusing a target protein to a scaffoldRead More…
Recent studies have revealed that extracellular vesicles (EVs) surface molecules are often accompanied by glycan or glycosylation modifications. Researchers from the Institute of Chemistry at the Slovak National Academy of Sciences haveRead More…
Small extracellular vesicles (sEVs) play a pivotal role as universal mediators of intercellular communication, emanating from diverse cell types. Despite extensive studies shedding light on the involvement of sEVs in various healthRead More…
It is well known that tumor metastasis relies on microenvironmental support from remote organs. However, the mechanisms through which metabolism regulates the tumor metastasis microenvironment remain undetermined. Recently, researchers discovered that lungRead More…
Extracellular vesicles (EVs)are a type of vesicle secreted by cells, characterized by a phospholipid bilayer structure. They carry a wealth of molecular information, including specific proteins, nucleic acids, lipids, and metabolites fromRead More…
Traditional liquid biopsies for cancer primarily rely on the detection of some recognized markers. However, during clinical use, many markers have limitations in statistical significance and robustness , leading to the removalRead More…
Prostate cancer is one of the most malignant tumors in men and remains incurable due to its heterogeneous and progressive nature. Genetic and epigenetic changes play important roles in prostate cancer development.Read More…
Extracellular vesicles (EVs), actively secreted from cancer cells and host cells into the circulation, are emerging as one of the front-runners in diagnostics for early cancer detection, disease monitoring, and treatment evaluation.Read More…
Tumor cell-derived extracellular vesicles (EVs) are being explored as circulating biomarkers for cancer detection. However, the effectiveness of bulk measurement in enabling early cancer detection remains uncertain. Professor Ralph Weissleder’s team fromRead More…