EGFRvIII

Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

Associated Disease
Anti-EGFRvIII CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC055 T cell Second 3C10 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC056 T cell Third 3C10 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC057 T cell Second 139 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC221 T cell Third 139 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC222 T cell Second 139 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC242 T cell Second MR1 ~8kb Lentiviral scFv--CD28-CD3ζ Mouse Inquiry
CAR-LC243 T cell Third MR1 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC271 T cell Second 139 ~8kb Lentiviral scFv-FRB/FKBP-41BB-CD3ζ Human Inquiry
CAR-LC272 T cell Second 139 ~8kb Lentiviral scFv-FKBP/FRB-41BB-CD3ζ Human Inquiry
CAR-LC379 T cell ~8kb Lentiviral scFv-CD28-41BB-CD70-CD3ζ Human Inquiry
CAR-MZ028 T cell Second RAbDMvIII ~8kb Lentiviral scFv-ICOS-CD3ζ Human Inquiry
CAR-MZ066 T cell First 3C10 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ067 T cell Second 3C10 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ068 T cell Second 3C10 ~8kb Lentiviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ069 T cell Third 3C10 ~8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ070 T cell First MR-1 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ073 T cell Third MR-1 ~8kb Retroviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ074 T cell Second L8A4 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ075 T cell Third L8A4 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ076 T cell Second L8A4 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ077 T cell First Y10 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ078 T cell Second Y10 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ079 T cell Second Y10 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ080 T cell Second Y10 ~8kb Retroviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ081 T cell First 131 ~8kb Retroviral scFv-CD3ζ Human Inquiry
CAR-MZ082 T cell Second 131 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ083 T cell Third 131 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ085 T cell Second 13.1.2 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ086 T cell Third 13.1.2 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ138 NK cell First MR1.1 ~8kb Lentiviral scFv-DAP12 Human Inquiry
CAR-MZ140 NK cell Second MR1.1 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ166 NK cell First MR1-1 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ167 NK cell Second MR1-1 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ168 NK cell First 225 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ169 NK cell Second 225 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-1-M315-2 T cell First RAbDMvIII 8kb Lentiviral scFv-CD28 Human Inquiry
CAR-T-1-M315-G T cell First RAbDMvIII 8kb Lentiviral scFv-FcεRIγ Human Inquiry
CAR-T-1-M315-Z T cell First RAbDMvIII 8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-T-2-M315-2G T cell Second RAbDMvIII 8kb Lentiviral scFv-CD28-FcεRIγ Human Inquiry
CAR-T-2-M315-2Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-2-M315-4G T cell Second RAbDMvIII 8kb Lentiviral scFv-CD4-FcεRIγ Human Inquiry
CAR-T-2-M315-4Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD4-CD3ζ Human Inquiry
CAR-T-2-M315-8Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD8-CD3ζ Human Inquiry
CAR-T-2-M315-BZ T cell Second RAbDMvIII 8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-T-2-M315-CZ T cell Second RAbDMvIII 8kb Lentiviral scFv-b2c-CD3ζ Human Inquiry
CAR-T-3-M315-2BZ T cell Third RAbDMvIII 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-3-M315-2XZ T cell Third RAbDMvIII 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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