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EGFRvIII

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-T-1-M315-2 Anti-EGFRvIII scFv h(CD28) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-YF076 Anti-EGFRvIII (CBL-YF022) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF022 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF077 Anti-EGFRvIII (CBL-YF022) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF022 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF390 Anti-EGFRvIII (MR1-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human MR1-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF429 Anti-EGFRvIII (MAb 139) h(-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF430 Anti-EGFRvIII (MAb 139) h(CD28-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF431 Anti-EGFRvIII (MAb 139) h(41BB-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF432 Anti-EGFRvIII (MAb 139) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-ZP8032 Anti-EGFRvIII (D2C7) h(CD28-CD3ζ) CAR, pCDCAR1 Human D2C7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8033 Anti-EGFRvIII (D2C7) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D2C7 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CARP-LX-036 Anti-EGFRvIII h(28ζ) CART, Combined with Kpt9274, a CAR Plus System Mouse CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-037 Anti-EGFRvIII h(28ζ) CART, Combined with Poly i:c, a CAR Plus System Mouse 806 CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-080 Anti-EGFRvIII h(BBζ) CART, Combined with Kpt9274, a CAR Plus System Mouse 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-081 Anti-EGFRvIII h(BBζ) CART, Combined with Poly i:c, a CAR Plus System Mouse 806 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CAR-SB-LX0210 Anti-EGFRvIII (CH806) h(CD28-CD3ζ) CAR, pSBCAR1 Human CH806 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0211 Anti-EGFRvIII (RAbDMvIII) h(CD28-CD3ζ) CAR, pSBCAR1 Human RAbDMvIII Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0212 Anti-EGFRvIII (CH12) h(CD28-CD3ζ) CAR, pSBCAR1 Human CH12 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
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