CAR Cell Products

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Chimeric antigen receptor (CAR) T cells are generated from healthy donors (allogeneic) or patient-derived T cells (autologous). After the T cells are expanded and genetically modified, they are reinfused into the patients. CAR T cell therapies use genetically engineered T cells to specifically target tumor cells, which offer a novel approach to cancer therapy. This innovative therapeutic approach has achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumors.

Our CAR Cells

CAR-γδ T Cells

Gamma-Delta (γδ) T cells are a distinct subset of T cells based on variable chains in the T cell receptor (TCR) protein complex. CAR γδ T cells at Creative Biolabs are engineered by incorporating a second-generation CAR into γδ T cells using the non-viral Sleeping Beauty (SB) transposon or CAR lentiviral transduction technology.

CAR-CIK Cells

Cytokine-induced killer (CIK) cells are a heterogeneous population of polyclonal T cells that acquire phenotypic and cytotoxic properties of natural killer (NK) cells through the cultivation process, becoming so-called T-NK cells. CAR-CIK cells at Creative Biolabs are engineered by incorporation of second-generation CAR into PBMC-derived CIK cells using the non-viral SB transposon or CAR lentivirus transduction technology.

CAR-iT Cells

As a starting source for CAR T cells, induced pluripotent Stem Cells (iPSCs) is an attractive approach to developing "off-the-shelf" CAR T-cell therapies. Creative Biolabs incorporates a second-generation CAR into iPSCs-derived T cells using lentiviral transduction technology to engineer the CAR-iT cells.

CAR-Treg Cells

Adoptive transfer of regulatory T cells (Tregs) can suppress lymphocytes against other antigens in the local microenvironment without destroying normal cells expressing the target antigen. Creative Biolabs incorporates a second-generation CAR into PBMC-derived Treg cells using lentiviral transduction technology to design CAR-Treg cells.

CAR Jurkat Cells

Jurkat cells are an immortal human leukemic T cell line widely used to examine T cell activation and signaling mechanisms. Creative Biolabs presents a cost-efficient and rapid method for evaluating CARs in human Jurkat T cells, which is anticipated to accelerate the discovery and improve the quality of candidate CAR-T cell therapies for future clinical applications.

TSCM CAR-T Cells

Stem cell memory T (TSCM) cells have high self-renewal ability, greater persistence, and comparable anti-tumor immunity in contrast to effector T (Teff) cells and effector memory T (Tem) cells. Recently, TSCM has served as a favorable type of source for ACT Adoptive cell therapy. Creative Biolabs specializes in engineering TSCM-based CAR T cells, incorporating special CAR into enriched TSCM cells to realize the enhancement of in vivo expansion and long-term remissions.

CAR Animal Cells

Animal cells serve as a critical integral part of CAR research, which can be widely used to engineer CAR animal cells. Creative Biolabs is committed to providing a variety of animal cell lines for CAR immunotherapy studies to treat refractory hematologic malignancies and solid tumors.

CAR-MA Cells

In the tumor microenvironment (TME), macrophages are the most abundant immune cells playing a key immunomodulation role in tumorigenesis and progression. Promisingly, the generation of CAR-engineered macrophage cell therapies (CAR-MA) will bring great therapeutic potential for intractable solid tumors. Leveraging years of experience in the field of CART, we are convinced to provide CAR-MA products according to the special needs of global customers.

Creative Biolabs offers wide range CAR cells type to meet your different needs at every step of your CAR research. Our cells have access to authentication which is vital importance for you to ensure your research can be trusted and reproducible. We follow the highest manufacturing standards and use the most reliable procedures in process control (IPC) and quality control (QC) to verify and authenticate every cell line.

Please browse the target below to find the right CAR cell product for you.

We have developed a proprietary online system for customizing CAR and CAR cell products, which offers full options to meet all unique needs, including but not limited to conventional or unconventional CAR constructs, as well as a variety of vectors and cells. The customization process can be completed with just a few simple clicks, please feel free to try it out.

CAR-Jurkat Cell Products

CAR-γδ T Cell Products

CAR-CIK Cell Products

CAR-iT Cell Products

CAR-Treg Cell Products

TSCM CAR-T Cell Products

CAR Animal Cell Products

CAR-MA Cell Products