Prostate cancer is one of the most malignant tumors in men and remains incurable due to its heterogeneous and progressive nature. Genetic and epigenetic changes play important roles in prostate cancer development.Read More…
The Emerging Role of Exosomes in Cancer Progression and Tumor Microenvironment Remodeling
Cancer stands as one of the leading causes of death globally, necessitating a deeper understanding of its progression factors. Exosomes, with an average size of 100 nm, serve as carriers of proteins,Read More…
Analysis of Single Extracellular Vesicles for Early Cancer Detection
Extracellular vesicles (EVs), actively secreted from cancer cells and host cells into the circulation, are emerging as one of the front-runners in diagnostics for early cancer detection, disease monitoring, and treatment evaluation.Read More…
Promoting or Inhibiting the Release of Extracellular Vesicles brings New Therapeutic Opportunities
Extracellular vesicles (EVs), released from various cell types under physiological and pathological conditions, are carriers of cell-to-cell communication. Recently, the Journal of Controlled Release published a review paper entitled ” Promotion orRead More…
Non-coding RNA and Extracellular Vesicles Help CAR-T Enhance the Efficacy of Solid Tumors
Poor tumor invasion, progression of exhaustion, and antigen insufficiency are common mechanisms that limit the efficacy of chimeric antigen receptor (CAR)-T cells. Delivery of pattern recognition receptor agonists is a strategy toRead More…
Exosomes Deliver Gene Vectors for Gene Therapy
Gene therapy is a therapy that treats genetic diseases by introducing genetic material (such as the expression system of therapeutic proteins or editing tools to correct wrong genes in diseased cells). TheRead More…
Drug Delivery – Extracellular Vesicles vs Synthetic Nanoparticles
Recently, a comment was published in the journal Nature Reviews Materials (impact factor 71.189), outlining the application of extracellular vesicles and synthetic nanoparticles in drug delivery. Synthetic nanoparticles have been widely usedRead More…
Exosomes – Role and Therapeutic Potential in Osteoarthritis
Abstract Exosomes are involved in many physiological and pathological processes by regulating cell-to-cell communication involved in various diseases including osteoarthritis (OA). Exosomes were detected in the joint cavity of humans and wereRead More…