Description
Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (T; cell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferase; gene under the control of nuclear factor of activator T cells (NFAT) response element.
Applications
This cell line is ideal for high throughput screening (HTS) to identify antagonistic monoclonal antibodies targeting either TIGIT or its ligands, such as CD155 in a cellular context.
Common Name
T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, VSTM3
Datasheet