Synthetic Gene Circuits for Cancer Immunotherapy - Turning Cancer Cells Against Themselves

Creative Biolabs offers fast and reliable support for any phase in the research of synthetic gene circuits for cancer immunotherapy, turning cancer cells against themselves. From project design to systematic assessment strategies, our seasoned scientists will work with you to develop a complete solution according to your special needs.

Synthetic Gene Circuits in Oncology

Building on the transformative assertion that engineering approaches, synthetic biology could be used to elucidate design principles of cellular systems and to implement synthetic digital for health applications. To enhance its capabilities to match therapeutic technologies to individual patients, synthetic biology streamlines the design and improves the strategies. Great improvements have opened the prospects for the availability of synthetic gene circuits, which might bring new capabilities to precision medicine in oncology.

Synthetic Gene Circuits for Cancer Immunotherapy - Turning Cancer Cells Against Themselves.

Potential Tumor-Associated Lymphatics in Cancer Immunotherapy

The lymphatic system is composed of a unidirectional hierarchy of vessels responsible for fluid homeostasis, lipid absorption, and the transport of immune cells and antigens to secondary lymphoid organs. Tumor lymphangiogenesis is a feature of many solid tumors. The density of tumor lymphatics is correlated with an increased incidence of lymph node metastasis in several cancers. Lymphatics serve both indirect and direct roles in the modulation of the host's adaptive immune response. In cancer, lymphatic proliferation and remodeling promote tumor dissemination. Functional lymphatics are necessary for generating an effective immune response. Lymphatic-dependent effects on the efficacy of immunotherapy have been paid more and more attention.

Synthetic Gene Circuits for Cancer Immunotherapy at Creative Biolabs

Scientists at Creative Biolabs have been engaged in the study of tumor lymphangiogenesis for many years. Accumulated evidence has shown that the induction of lymphangiogenesis can enhance cancer immunotherapy and boost T cell response. We are proficient at inspiring the lymphangiogenic potentiation of immunotherapy to turn cancer cells against themselves.

Cancer cells, both immortalized cell lines and primary cancer cells, are invaluable biological tools. They have enabled many significant breakthroughs in oncology research, and continue to be incredibly useful. We are proud to launch our cancer cell engineering service. A range of cancer cells is available for self-destruction purposes.

Leukemia Cells Pancreatic Cancer Cells Colorectal Cancer Cells Prostate Cancer Cells Liver Cancer Cells Breast Cancer Cells
Lung Cancer Cells Gastric Cancer Cells Ovarian Cancer Cells Melanoma Cells Neuroblastoma Cells

We have developed several effective Strategies for cancer cell engineering.

Different Genetic Methods for engineering cancer cells for self-destruction are available, including:

What's more, it is important to assess the effect of self-destruction cancer cells. We also offer high-quality Self-destruction Assays according to our client's specific needs.

Furthermore, Creative Biolabs also offers high-quality custom services of Ex Vivo Immune Reactivity Assessment and Toxicity Assessment. For more detailed information, please feel free to contact us or directly send us an inquiry.

References

  1. Re, A. Synthetic gene expression circuits for designing precision tools in oncology. Frontiers in Cell and Developmental Biology. 2017, 5: 77.
  2. Li, C.Y.; et al. Lymphatics in tumor progression and immunomodulation. International Journal of Molecular Sciences. 2022, 23(4): 2127.

For Research Use Only | Not For Clinical Use

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