Gut Microbiota-based Diagnostics Platform

The Human Microbiome Project has spurred many scientists to study the complex interactions and impact of microorganisms on health. Research in gut microbiota is providing new insights into the development of diagnostics. Developing new diagnostic methods will provide an accurate assessment of the taxonomic compositions of microbiomes associated with diverse diseases. Creative Biolabs combines a cutting-edge gut microbiota-based diagnostics platform with a team of tenured scientists who are experts in gut microbial biomarker discovery, analysis and characterization, gut microbiome model development, and gut microbiota & host interaction study.

Background

Specific biomarkers are rapid and make it possible to identify groups of patients compromised with various types of complications. The gut microbiota is a major contributor to the pathophysiological process and maybe a potential early biomarker. The development of diagnostic tools based on gut microbiota biomarkers to regulate the intestinal microbial ecosystem is probably the most exciting frontier. There is no doubt about the wide and deep impact of gut microbiota on a number of body functions in the host. It is impressive that gut microbes can affect brain injury after stroke. Changes in the composition of the gut microbiota can reduce the volume of brain infarcts substantially after occlusion of the cerebral artery.

Technologies for Gut Microbiota Research

Advancements in our understanding of the gut microbiome are leading to new ideas regarding the diagnosis and management of related diseases. Next-generation sequencing (NGS), mass spectrometry, immunoassays, and protein array will facilitate the application of gut microbiome science to medical microbiology and clinical chemistry. Biomedical advances in the human gut microbiome will result in new diagnostic and disease monitoring strategies.

Services Available

Creative Biolabs has built a team of experienced scientists who are skilled in microbiome sample preparation, microbiome data processing, and statistical analysis. The goal of our gut microbiome study is to understand the role of microbes in health and disease, discover biomarkers, and then design an effective diagnostic strategy. We will determine the diversity of intestinal microbiota and its correlation with clinical parameters in patients and healthy subjects, and assess the importance of intestinal microbiota in patients. Moreover, we also identify the features of changes in the gut microbiota and biomarkers in patients after treatment and assess their relationship with postoperative complications.

Our comprehensive portfolio provides reliable and accurate gut microbiota analysis to help our clients’ meaningful project development. For more detailed information, please feel free to contact us or directly send us an inquiry.

Reference

  1. Versalovic, J.; et al. Microbiome-based diagnostics: ready for applications in laboratory medicine?. Clinical Chemistry. 2017, 63(11):1674-9.

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