Short Description
Quantifies total sialic acid (N-acetylneuraminic acid) on glycoproteins.
Development Stage
Research-Grade Lipid Metabolism Assay Development
Description
The LipidFlux™ Sialic Acid Assay Kit quantifies total sialic acid on glycoproteins, serving as a critical quality control tool for recombinant therapeutic proteins. This assay is also used to assess sialylation patterns, which are key markers of inflammation and tumor progression in diagnostic research. By validating the consistency of glycosylation, it ensures the efficacy and safety of biologic drugs.
Features
Detects both free and bound sialic acid; Supports quality control of recombinant therapeutic glycoproteins.
Process Relevance
Biologics Quality Control (Glycosylation)
Application Stage
Manufacturing / QC
Applications
Assessing glycoprotein sialylation in inflammation and cancer diagnostics.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum, citrate-plasma, urine, cell lysate, culture medium
Research Areas
Inflammation; Bioprocessing (Glycosylation)
Datasheet