ModifiSite™ Aspartate Transaminase Assay Kit

CAT#: ITS-1125-HM12
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Measures AST activity to assess liver and heart tissue damage.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
Used in conjunction with ALT assays, the ModifiSite™ Aspartate Transaminase Assay Kit calculates hepatotoxicity ratios to provide a comprehensive view of tissue damage in systemic toxicity studies. This rapid kinetic determination supports high-volume toxicity screening, allowing for the efficient evaluation of lead compounds. It is an integral component of standard liver and cardiac safety assessment batteries in pharmaceutical research.
Features
Rapid kinetic determination supports high-volume toxicity screening; Integral component of standard liver and cardiac safety assessment batteries.
Process Relevance
Hepatotoxicity Screening (Systemic)
Application Stage
Pre-clinical Safety
Applications
Used alongside ALT for computing the AST/ALT ratio in clinical diagnostics.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 340 nm
Sample Type
Serum, plasma samples
Research Areas
Hepatology; Toxicology
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 10 min
LOD
2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Aspartate Transaminase (AST) facilitates the interconversion of aspartate and alpha-ketoglutarate. While found in the liver it is also abundant in cardiac and skeletal muscle; elevated levels indicate tissue damage in these organs.
For Research Use Only | Not For Clinical Use
Online Inquiry