Target: Quantitatively detects urinary indoxyl sulfate (indican) as a marker of gastrointestinal bacterial putrefaction.
Brand: OXPHOSight
Development Stage: Research-Grade Metabolic Assay Development
Short Description
Quantifies urinary indican levels using a modified Obermayer colorimetric method.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Urinary Indican Test Kit offers a fast and cost-effective screening tool for detecting protein putrefaction and gastrointestinal dysbiosis. By identifying elevated indican levels associated with bacterial overgrowth and malabsorption, this kit supports pre-clinical research into digestive health and intestinal toxemia, providing critical insights for optimizing nutritional and therapeutic interventions.
Features
Rapid Diagnostic Turnaround: This optimized assay provides high-precision results within a 15-minute window, accelerating decision-making in high-throughput environments. Refined Chemical Safety: Utilizing a modernized Obermeyer formulation, our kit reduces hazardous exposure while maintaining superior analytical sensitivity. Simplified Direct Protocol: The intuitive "mix-and-read" format requires only 2 mL of sample, eliminating complex pretreatment or specialized instrumentation.
Process Relevance
This kit facilitates rapid screening of protein putrefaction to validate gastrointestinal integrity during metabolic research and therapeutic trials.
Application Stage
Ideal for preclinical drug discovery, clinical metabolic profiling, and longitudinal monitoring of intestinal dysbiosis in patient cohorts.
Applications
The assay is utilized for quantifying bacterial tryptophan deconjugation in urine, supporting research into SIBO, malabsorption, and the efficacy of probiotic interventions.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Quantitatively detects urinary indoxyl sulfate (indican) as a marker of gastrointestinal bacterial putrefaction.
Detection Method
Obermeyer (Improved)
Sample Type
Urine
Research Areas
Gastrointestinal physiology, microbiome-host interactions, nutritional biochemistry, metabolic syndrome research, etc.
Size
20 tests
Data Output Type
Qualitative or semi-quantitative visual colorimetric assessment based on a standardized 0-4 scale color chart.
Assay Time
15 min
Species
Human
Storage
Store at room temperature upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Keep containers tightly sealed and avoid prolonged exposure to direct sunlight or excessive heat. Ensure components are stored in a dry, well-ventilated area to maintain stability throughout the shelf life.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped at room temperature.
Background
Urinary indican serves as a vital biomarker for intestinal toxemia and protein maldigestion. It originates from bacterial breakdown of dietary tryptophan, reflecting the balance between host enzymatic digestion and microbial putrefaction.
Pathways
In the gut, bacteria convert tryptophan into indole, which is absorbed and sulfated in the liver. This metabolic pathway culminates in the renal excretion of indoxyl sulfate (indican) for biological monitoring.