ModifiSite™ β-N-Acetylglucosaminidase Assay Kit

CAT#: ITS-1125-HM60
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Measures NAG activity, a renal damage marker.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ β-N-Acetylglucosaminidase Assay Kit provides a sensitive urinary biomarker for detecting early-stage renal tubular toxicity in pharmaceutical development. This high-throughput compatible assay allows for the non-invasive monitoring of kidney injury during nephrotoxicity screening. It is an essential component of safety panels, ensuring that new drug candidates do not cause sub-clinical renal damage.
Features
High-throughput compatible; Sensitive urinary biomarker for early-stage renal tubular toxicity in drug development.
Process Relevance
Early Kidney Injury Biomarker
Application Stage
Pre-clinical Safety
Applications
Early detection of renal tubular damage and nephrotoxicity.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 405 nm
Sample Type
Urine, serum, plasma, cell lysate, samples
Research Areas
Nephrology (Toxicology)
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 30 min
LOD
0.2 U/L
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
N-Acetyl-beta-D-glucosaminidase (NAG) is a lysosomal enzyme found in renal proximal tubules. Its presence in urine is a sensitive early marker of renal tubular damage caused by nephrotoxic drugs.
For Research Use Only | Not For Clinical Use
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