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ActivatorPep™ NY-ESO-1, human-L (CA-LX044)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Specific Inquiry

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  • Product Name
  • ActivatorPep™ NY-ESO-1, human-L
  • Cat. No.
  • CA-LX044
  • Product Summary
  • Creative Biolabs provides an extensive cell activation reagents including Expansion Kits and Activator peptides for global custom, which are suitable to many applications, such as in vitro stimulation antigen-specific cells. NY-ESO-1 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the complete sequence of the human NY-ESO-1 protein (UniProt ID: P78358). Which can be used for in vitro stimulation of NY-ESO-1-specific CD4+ and CD8+ T cells.
  • Background Information
  • NY-ESO-1 belongs to the cancer-testis family of antigens. It is highly expressed in male germ cells but generally not in other normal tissues. Aberrant expression is found in a variable proportion of a wide range of different cancer types. Patients with advanced NY-ESO-1-expressing tumors frequently develop humoral and cellular immunity to NY-ESO-11. NY-ESO is an attractive antigen to monitor anti-tumor immune responses and is used for immunotherapeutic interventions.
  • Applications
  • Stimulation Reagents
  • Cross-reactivity
  • No significant cross-reactivity was observed among analytes in this panel.
  • Species Reactivity
  • Human
  • Purity or Quality Grade
  • Research Grade
  • Downstream Application
  • Pulsing of antigen-presenting cells for research;
    Detection and analysis of antigen-specific CD4+ and CD8+ effector/memory T cells in PBMCs;
  • Product Size
  • for stimulation of 1×109 cells
  • Shipping Condition
  • The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Storage Conditions
  • Store at -20°C.
  • Shelf life
  • > 6 Months from date of receipt under proper storage condition.
  • Product Use Statement
  • For research use only, not for diagnostic or therapeutic use.
  • Product Features
  • Efficient expansion and increased survival rate of Ag-specific T cells;
    Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells;
  • Principle of the Assay
  • NY-ESO-1 peptide pools have been developed for the efficient in vitro stimulation of antigen-specific CD4+ and CD8+ T cells as peptides of 15-aa length with 11-aa overlap represent an optimized solution for stimulating both CD4+ and CD8+ T cells in various applications.
  • Research Category
  • Immunology
  • Panel Type
  • Stimulation for CD4+ and CD8+ T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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