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The integration of synthetic antigen receptors into immune cells has emerged as a powerful therapeutic strategy for treating various diseases, with T cells engineered to express chimeric antigen receptors (CAR) being a notable example for targeted cancer therapy. However, in addition to T lymphocytes, B lymphocytes have also shown promise as immune cells that can be genetically engineered for therapeutic purposes. One such approach involves using CAR-B cells to deliver monoclonal antibodies to tumor sites by targeting specific tumor-associated antigens (TAA).
Creative Biolabs has established a novel chimeric B cell receptors (CBCR) cell platform based on B leukemic cell line NALM6 to investigate the potential of CBCRs as a vehicle for adoptive immune cell therapies. B leukemic cell line NALM6 are genomically modified with the Anti-B7-H3 CBCR vector (Cat.# XS-0323-ZP823). The expression of CBCR is then detected to confirm the precise integration of the anti-B7-H3 CBCR into the appropriate locus of the B leukemic cell line NALM6.
There are currently no customer reviews or questions for Anti-B7-H3 (BRCA84D scFv-CD79β) CBCR, NALM6 (XS-0323-ZP2535). Click the button below to contact us or submit your feedback about this product.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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