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Anti-Cytochrome P450 T cell receptor (JL12), pCDTCR1 (TCR-C037Z)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-Cytochrome P450 T cell receptor (TCR) is constructed for the engineering of T cell to target Human Cytochrome P450. The T cells are genetically modified through transduction with a lentiviral vector expressing Cytochrome P450-specific T cell receptor.

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Details

  • Target
  • Cytochrome P450
  • Target Species
  • Human
  • Epitope
  • KPIVVLHGY
  • Format
  • Non-modified
  • Allele
  • HLA-B35
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • TCR Clone
  • JL12
  • Host Species
  • Human

Target

  • Official Symbol
  • Cytochrome P450
  • Introduction
  • Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins. CYPs use a variety of small and large molecules as substrates in enzymatic reactions. They are, in general, the terminal oxidase enzymes in electron transfer chains, broadly categorized as P450-containing systems. The term P450 is derived from the spectrophotometric peak at the wavelength of the absorption maximum of the enzyme (450 nm) when it is in the reduced state and complexed with carbon monoxide.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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