Human Flt-3 CAR Detection Reagent, Fc Tag (FITC) (XS-0423-LX39)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Human Flt-3 CAR Detection Reagent, Fc Tag (FITC) is applied for evaluating Human Flt-3 CAR expression, and is suitable for FC application.

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Specifications

Target
Flt-3

Organism
Human

Application
Used for evaluating CAR expression

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
The optimal working dilutions should be determined by the end user.

Molecular Characterization
The CAR detection reagent contains AA Asn 27 - Ser 543 of Human Flt-3.

Conjugation
FITC

Size
25 tests; 100 tests

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
HEK293 cell

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.

Target Alternative Names
fms related receptor tyrosine kinase 3

Entrez Gene ID
2322

UniProt ID
AAH14785.1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Human Flt-3 CAR Detection Reagent, Fc Tag (FITC) (XS-0423-LX39)

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Specifications

Target

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