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Human Siglec-3 CAR Detection Reagent, Fc Tag (FITC) (XS-0423-LX50)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Human Siglec-3 CAR Detection Reagent, Fc Tag (FITC) is applied for evaluating Human CD33 CAR expression, and is suitable for FC application.

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Specifications

  • Target
  • Siglec-3
  • Organism
  • Human
  • Application
  • Used for evaluating CAR expression
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    Please protect from light and avoid repeated freeze-thaw cycles.
  • Shelf-Life
  • Stable as supplied until expiry date on label.
  • Application Notes
  • The optimal working dilutions should be determined by the end user.
  • Diseases
  • Acute lymphoblastic leukemia (ALL)
  • Molecular Characterization
  • The CAR detection reagent contains AA Asp 18 - His 259 of Human CD33.
  • Conjugation
  • FITC
  • Size
  • 25 tests; 100 tests
  • Formulation
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
  • Expression
  • HEK293 cell
  • Host Species
  • Human
  • Species Reactivity
  • Human
  • Form
  • Lyophilized

Target

  • Target Introduction
  • CD33 (CD33 Molecule) is a Protein Coding gene.
    Diseases associated with CD33 include Gallbladder Lymphoma and Extracutaneous Mastocytoma.
    Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineagespecific Markers and Innate Immune System.
    Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding.
    An important paralog of this gene is SIGLEC6.
  • Target Alternative Names
  • CD33 Molecule
  • Entrez Gene ID
  • 945

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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