Systems featuring programmable RNA molecule export capabilities hold the potential for non-destructive cellular dynamics monitoring and efficient RNA delivery to engineered cells. In a recent breakthrough, Michael B. Elowitz and Felix HornsRead More…
The Value of Glycosylation Modifications on Extracellular Vesicles in Vesicle Isolation Analysis and Clinical Detection
Recent studies have revealed that extracellular vesicles (EVs) surface molecules are often accompanied by glycan or glycosylation modifications. Researchers from the Institute of Chemistry at the Slovak National Academy of Sciences haveRead More…
Extracellular Vesicles in Fatty Liver Promote a Metastatic Tumor Microenvironment
Non-alcoholic fatty liver disease (NAFLD) is strongly linked to various cancers, including liver, breast, prostate, pancreatic, and colorectal cancer, surpassing its association with obesity alone. Patients with fatty liver disease exhibit aRead More…
The Role of Extracellular Vesicles in Cancer and Future Prospects
Intercellular communication stands as a pivotal characteristic in tumor progression and metastasis. Extracellular vesicles (EVs), generated by diverse cells including tumor cells, serve as indispensable agents in cell-to-cell communication. They wield influenceRead More…
An Article to Understand the Basic Background of Exosome Research
Exosomes Exosomes are single-layer membrane vesicles secreted by cells with a diameter of 30-200 nm, rich in proteins, lipids, nucleic acids, and carbohydrate complexes, and have obvious molecular heterogeneity. The production ofRead More…
The Complexity of Current Research on Extracellular Vesicles and Nanoparticles
Research on extracellular vesicles (EVs) and nanoparticles (NPs) is increasing rapidly, with recent years unveiling unprecedented complexity and diversity in vesicles. Consequently, our comprehension of cellular biology facilitated by the release ofRead More…
Single-Molecule Localization Microscopy for Investigating Small Extracellular Vesicles
Small extracellular vesicles (sEVs) play a pivotal role as universal mediators of intercellular communication, emanating from diverse cell types. Despite extensive studies shedding light on the involvement of sEVs in various healthRead More…
Lung Mesenchymal Cells Secrete Lipids through Exosome-Like Vesicles to Promote Breast Cancer Lung Metastasis
It is well known that tumor metastasis relies on microenvironmental support from remote organs. However, the mechanisms through which metabolism regulates the tumor metastasis microenvironment remain undetermined. Recently, researchers discovered that lungRead More…
Exosomes—Nature’s Lipid Nanoparticles: A Rising Star in Drug Delivery and Diagnostics
Exosomes, nanoscale extracellular vesicles enveloped by a lipid bilayer membrane and secreted by most eukaryotic cells, possess unique characteristics, including inherent stability, low immunogenicity, biocompatibility and excellent biological properties. Their membrane penetrationRead More…
Ultrasensitive and Biomimetic 3D Recognition Technology for Visualizing Extracellular Vesicles with 2D Flexible Nanostructures
Extracellular vesicles (EVs)are a type of vesicle secreted by cells, characterized by a phospholipid bilayer structure. They carry a wealth of molecular information, including specific proteins, nucleic acids, lipids, and metabolites fromRead More…
