Non-alcoholic fatty liver disease (NAFLD) is strongly linked to various cancers, including liver, breast, prostate, pancreatic, and colorectal cancer, surpassing its association with obesity alone. Patients with fatty liver disease exhibit aRead More…
Intercellular communication stands as a pivotal characteristic in tumor progression and metastasis. Extracellular vesicles (EVs), generated by diverse cells including tumor cells, serve as indispensable agents in cell-to-cell communication. They wield influenceRead More…
Exosomes Exosomes are single-layer membrane vesicles secreted by cells with a diameter of 30-200 nm, rich in proteins, lipids, nucleic acids, and carbohydrate complexes, and have obvious molecular heterogeneity. The production ofRead More…
Research on extracellular vesicles (EVs) and nanoparticles (NPs) is increasing rapidly, with recent years unveiling unprecedented complexity and diversity in vesicles. Consequently, our comprehension of cellular biology facilitated by the release ofRead More…
Small extracellular vesicles (sEVs) play a pivotal role as universal mediators of intercellular communication, emanating from diverse cell types. Despite extensive studies shedding light on the involvement of sEVs in various healthRead More…
It is well known that tumor metastasis relies on microenvironmental support from remote organs. However, the mechanisms through which metabolism regulates the tumor metastasis microenvironment remain undetermined. Recently, researchers discovered that lungRead More…
Exosomes, nanoscale extracellular vesicles enveloped by a lipid bilayer membrane and secreted by most eukaryotic cells, possess unique characteristics, including inherent stability, low immunogenicity, biocompatibility and excellent biological properties. Their membrane penetrationRead More…
Extracellular vesicles (EVs)are a type of vesicle secreted by cells, characterized by a phospholipid bilayer structure. They carry a wealth of molecular information, including specific proteins, nucleic acids, lipids, and metabolites fromRead More…
Exosomes, derived from multivesicular bodies, exhibit a cup-shaped under electron microscopy, with diameters ranging from 50 to 150 nanometers. Loaded with various contents, including nucleic acids, proteins, lipids, enzymes and metabolites. TheseRead More…
Traditional liquid biopsies for cancer primarily rely on the detection of some recognized markers. However, during clinical use, many markers have limitations in statistical significance and robustness , leading to the removalRead More…