NEXT™ CAR-T In Vitro Validation

At Creative Biolabs, our scientists will perform a professional multiplex assessment of successfully transfected TCR-T and CAR-T/NK/MA cells to validate their structural robustness and biological functions in vitro. With advanced technology and experiences, Creative Biolabs' scientists can design and implement a full range of validation analysis services based on your cell therapy engineering goals. The detailed validation methods are as follows:

Steps in Cellular and Gene Therapy

Steps in Cellular and Gene Therapy

TCR/CAR Expression Analysis >

To assess TCR/CAR expression at various stages after gene transfection, cell preparation and clinical treatment …

Single Cell Immune Profiling >

To identify several immune cells, such as CAR-T cells, CAR-NK cells, CAR-MA cells, adjuvant and regulatory …

Phenotype Analysis >

To detect cell performance and behavior such as apoptosis, necrosis, proliferation, stagnation, invasion, migration …

Cytokine Release Assay >

To identify several immune cells, such as CAR-T cells, CAR-NK cells, CAR-MA cells, adjuvant and regulatory …

Cell Exhaustion Assay >

To analyze multiple phenotypes and functional parameters for CAR-T/NK cell exhaustion by mimicking the tumor …

Immunometabolism Assay >

To perform a variety of accurate and direct cellular metabolic analyses in a 96-well plate and the results analyzed by …

Cytotoxicity Assay >

To assess of the cytotoxicity/safety for a wide range of cells and compounds by using a wide range of cancer and …

CAR-MA Phagocytosis Assay >

To measure the phagocytosis of cellular ‘substrate’ including red blood cells, E. coli and zymosan (yeast) particles …

In Vitro Anti-Tumor Efficacy >

To monitor tumor cell proliferation and death to measure the killing immune response to tumor cells based on 96-well plate …

Please feel free to contact us for more detailed information.

For Research Use Only | Not For Clinical Use

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