Target | AKT2 |
Immunogen | human v-akt murine thymoma viral oncogene homolog 2 |
Species Reactivity | Human |
Application | IP, FC, ChIP, Neut, Cell Penetration |
Clone | WJ183 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
Target Synonym | AKT2; v-akt murine thymoma viral oncogene homolog 2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA |
Gene ID | 208 |
UniProt ID | B4DG79 |
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