Target | APOA1 |
Immunogen | human apolipoprotein A-1 |
Species Reactivity | Human |
Application | WB, ELISA, IP, FuncS, Cell Penetration |
Clone | WJ197 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. |
Target Synonym | APOA1; apolipoprotein A-I; apo-AI |
Gene ID | 335 |
UniProt ID | A0A024R3E3 |
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