Super™ Llama Anti-APP Single Domain Antibody-snGFP (WJ200)(Cat#: MDWJ2150)
This product is a Llama single domain antibody recognizes APP conjugated to snGFP. This product has the ability for cell penetration.
Datasheets| Target | APP |
| Immunogen | Human amyloid beta (A4) precursor prot |
| Species Reactivity | Human |
| Application | IP, IF, FuncS, Cell Penetration |
| Clone | WJ200 |
| Host Animal | Llama |
| Isotype | sdAb |
| Clonality | Monoclonal |
| Class | Primary |
| Concentration | 1 mg/mL |
| Conjugation | snGFP |
| Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
| Target Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Target Synonym | APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheim |
| Gene ID | 351 |
| UniProt ID | P05067 |
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KINDLY NOTE
- Some properties of custom products can be tailored flexibly. Please feel free to send your specific demands through an inquiry.
- All listed customized sdAb products are for lab research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use. For commercial purpose, please review our one-stop solutions for de novo sdAb discovery.
- No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
- NCBI/UniProt data is used to refer general target information. It may not necessarily be applicable to one specific product.
- Creative Biolabs has made every effort to ensure the accuracy of the datasheet and reserves the right to make changes to the datasheet at any time without prior notice. Creative Biolabs will not be liable for any omissions or errors contained herein, please use the COA of your custom products as standard.
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For Research Use Only. Not for diagnostic or therapeutic applications.
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