Target | BCL2 |
Immunogen | human B-cell CLL/lymphoma 2 |
Species Reactivity | Human |
Application | WB, ELISA, IP, FuncS, Cell Penetration |
Clone | WJ221 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. |
Target Synonym | BCL2; B-cell CLL/lymphoma 2; Bcl-2; PPP1R50; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50 |
Gene ID | 596 |
UniProt ID | A0A024R2B3 |
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