Target | BMP4 |
Species Reactivity | Human |
Application | ELISA, Cell Penetration |
Clone | E7 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | sp-mNeptune |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This gene encodes a member of the bone morphogenetic protein (BMP) family of proteins, which is part of the transforming growth factor-beta (TGF-beta) superfamily. Members of the BMP family play an important role in bone and cartilage development. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. Alternative splicing results in multiple transcript variants. |
Target Synonym | Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 2B; BMP-2B; BMP2B; BMP-4; BMP2B1; MCOPS6; OFC11; Zyme; DVR4 |
Gene ID | 652 |
UniProt ID | P12644 |
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