Super™ Human Anti-CD274 Single Domain Antibody-sn-mNeptune (PDL1-56dAb)(Cat#: MDWJ2761)
This product is a Human single domain antibody recognizes CD274 conjugated to sn-mNeptune. This product has the ability for cell penetration.
Datasheets| Target | CD274 |
| Species Reactivity | Human |
| Application | ELISA, FC, BL, Cell Penetration |
| Clone | PDL1-56dAb |
| Host Animal | Human |
| Isotype | sdAb |
| Clonality | Monoclonal |
| Class | Primary |
| Concentration | 1 mg/mL |
| Conjugation | sn-mNeptune |
| Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
| Target Background | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. |
| Target Synonym | CD274 Molecule; CD274 Antigen; B7 Homolog 1; Programmed Cell Death 1 Ligand 1; PDCD1 Ligand 1; PDCD1LG1; PDCD1L1 |
| Gene ID | 29126 |
| UniProt ID | Q9NZQ7 |
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KINDLY NOTE
- Some properties of custom products can be tailored flexibly. Please feel free to send your specific demands through an inquiry.
- All listed customized sdAb products are for lab research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use. For commercial purpose, please review our one-stop solutions for de novo sdAb discovery.
- No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
- NCBI/UniProt data is used to refer general target information. It may not necessarily be applicable to one specific product.
- Creative Biolabs has made every effort to ensure the accuracy of the datasheet and reserves the right to make changes to the datasheet at any time without prior notice. Creative Biolabs will not be liable for any omissions or errors contained herein, please use the COA of your custom products as standard.
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For Research Use Only. Not for diagnostic or therapeutic applications.
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