Target | CFL1 |
Immunogen | human cofilin 1 (non-muscle) |
Species Reactivity | Human |
Application | FuncS, IP, ChIP, Cell Penetration |
Clone | WJ282 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Target Synonym | CFL1; cofilin 1 (non-muscle); CFL; cofilin; HEL-S-15; cofilin-1; 18 kDa phosphoprotein; cofilin, non-muscle isoform; epididymis secretory protein Li 15; p18 |
Gene ID | 1072 |
UniProt ID | P23528 |
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