Target | CXCL12 |
Immunogen | The chemokine cocktail ( a mix of recombinant human CCL2/MCP1 (Mucin stalk Chimera) carrier free, recombinant human CCL3/MIP1 alpha earner free, recombinant human CCL5/RANTES (Mucin stalk Chimera) carrier free, recombinant human CXCLl 1/I-TAC carrier free, and recombinant human CXCLl 2/SDF1 alpha carrier free) |
Species Reactivity | Human |
Application | FuncS, Cell Penetration |
Clone | 12A4 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. |
Target Synonym | Chemokine (C-X-C Motif) Ligand 12; Pre-B Cell Growth-Stimulating Factor; Intercrine Reduced In Hepatomas; SDF1; PBSF; IRH; Stromal Cell-Derived Factor 1; C-X-C Motif Chemokine 12; SCYB12; HSDF-1; TPAR1; SDF1A; SDF1B; SDF-1; TLSF; HIRH |
Gene ID | 6387 |
UniProt ID | P48061 |
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