Target | E. cloacae blaTEM-1b |
Immunogen | Enterobacter cloacae TEM-1 beta-lactamase |
Species Reactivity | E. cloacae |
Application | ELISA, IHC, FC, FuncS, Cell Penetration |
Clone | WJ324 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | sn-mNeptune |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | Beta-lactamases are enzymes (EC 3.5.2.6) produced by some bacteria that provide resistance to β-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties. Enterobacter cloacae is a clinically significant Gram-negative, facultatively-anaerobic, rod-shaped bacterium. |
Target Synonym | E. cloacae blaTEM-1b; TEM-1 beta-lactamase; blaTEM-1b; E. cloacae; Enterobacter cloacae; Enterobacter cloacae TEM-1 beta-lactamase |
Gene ID | 13919456 |
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