Target | E. coli F4 fimbriae |
Immunogen | Escherichia coli F4 fimbriae |
Species Reactivity | E. coli |
Application | WB, IP, ChIP, Neut, ELISA, Cell Penetration |
Clone | WJ328 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | sn-mNeptune |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | F4 or K88 fimbriae are long filamentous polymeric surface proteins of enterotoxigenic Escherichia coli (ETEC), consisting of so-called major (FaeG) and minor (FaeF, FaeH, FaeC, and probably FaeI) subunits. Several serotypes of F4 have been described, namely F4ab, F4ac, and F4ad. The F4 fimbriae allow the microorganisms to adhere to F4-specific receptors present on brush borders of villous enterocytes and consequently to colonize the small intestine. Such ETEC infections are responsible for diarrhea and mortality in neonatal and recently weaned pigs. |
Target Synonym | F4 fimbriae; K88 fimbriae; E. coli F4 fimbriae; E. coli K88 fimbriae |
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