Target | E. coli Stx1A |
Immunogen | Escherichia coli Shiga Toxins 1 |
Species Reactivity | E. coli |
Application | WB, ELISA, IP, FuncS, Cell Penetration |
Clone | WJ335 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | spGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Target Synonym | STX1A; syntaxin 1A (brain); STX1; HPC-1; P35-1; SYN1A; syntaxin-1A; neuron-specific antigen HPC-1 |
Gene ID | 6804 |
UniProt ID | Q16623 |
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