Target | Fcer1g |
Immunogen | human Fc receptor, IgE, high affinity I, gamma polypeptide |
Species Reactivity | Human |
Application | WB, ELISA, IP, FuncS, Cell Penetration |
Clone | WJ363 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. |
Target Synonym | FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide; CD23; Fce1g; Ly-50; FcR[g]; AI573376; FcRgamma; FcR-gamma; FcepsilonRI; high affinity immunoglobulin epsilon receptor subunit gamma; fceRI gamma; fc-epsilon RI-gamma; Fc receptor gamma-chain; i |
Gene ID | 14127 |
UniProt ID | P20491 |
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