Super™ Llama Anti-H. pylori ureA Single Domain Antibody-snGFP (WJ405)(Cat#: MDWJ3905)

This product is a Llama single domain antibody recognizes H. pylori ureA conjugated to snGFP. This product has the ability for cell penetration.

Target	H. pylori ureA
Immunogen	Helicobacter pylori urease subunit alpha
Species Reactivity	H. pylori.
Application	ELISA, IHC, FC, FuncS, Cell Penetration
Clone	WJ405
Host Animal	Llama
Isotype	sdAb
Clonality	Monoclonal
Class	Primary

Concentration	1 mg/mL
Conjugation	snGFP
Storage Condition	Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target Background	Ureases (EC 3.5.1.5), functionally, belong to the superfamily of amidohydrolases and phosphotriesterases. It is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows: (NH2)2CO + H2O → CO2 + 2NH3 More specifically, urease catalyzes the hydrolysis of urea to produce ammonia and carbamate; the carbamate produced is subsequently degraded by spontaneous hydrolysis to produce another ammonia and carbonic acid. Urease activity tends to increase the pH of its environment as it produces ammonia, a basic molecule. Ureases are found in numerous bacteria, fungi, algae, plants and some invertebrates, as well as in soils, as a soil enzyme. They are nickel-containing metalloenzymes of high molecular weight. In 1926, James B. Sumner, an assistant professor at Cornell University, showed that urease is a protein by examining its crystallized form. Sumner's work was the first demonstration that a pure protein can function as an enzyme, and led eventually to the recognition that most enzymes are in fact proteins, and the award of the Nobel prize in chemistry to Sumner in 1946. The structure of urease was first solved by P. A. Karplus in 1995. Urease was the first ever enzyme crystallized.
Target Synonym	ureA; urease subunit alpha; H. pylori ureA; Helicobacter pylori urease subunit alpha; Helicobacter pylori; H. pylori
Gene ID	900171
UniProt ID	P14916

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KINDLY NOTE

Some properties of custom products can be tailored flexibly. Please feel free to send your specific demands through an inquiry.
All listed customized sdAb products are for lab research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use. For commercial purpose, please review our one-stop solutions for de novo sdAb discovery.
No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
NCBI/UniProt data is used to refer general target information. It may not necessarily be applicable to one specific product.
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For Research Use Only. Not for diagnostic or therapeutic applications.