Target | HIV-1 |
Immunogen | human immunodeficiency virus-1 |
Species Reactivity | HIV |
Application | WB, ICC, ChIP, ELISA, Cell Penetration |
Clone | WJ428 |
Host Animal | Llama |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability. HIV can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the endangered west African primate sooty mangabey. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data. Some of the subtypes are known to be more virulent or are resistant to different medications. HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only a few of them are functional. |
Target Synonym | HIV-1 p24; HIV1 p24; CA; Capsid protein p24; Human immunodeficiency virus 1; Human immunodeficiency virus type 1 p24; Retroviridae; Lentivirus; HTLV3; Human Immunodeficiency Virus 1; Group VI (ssRNA-RT); Human immunodeficiency virus; HIV |
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