Target | Phosphorylated MAPT |
Immunogen | The single phospho-peptide derived from the C-terminus of a tau protein of sequence CSIDMVDS(P03H2)PQLATLAD or a phospho-tau enriched Alzheimer's disease brain extract from a human |
Species Reactivity | Human, Mouse |
Application | ELISA, IHC, WB, IF, FuncS, Cell Penetration |
Clone | Tau-A2 (A2) |
Host Animal | Alpaca |
Isotype | sdAb |
Clonality | Monoclonal |
Class | Primary |
Concentration | 1 mg/mL |
Conjugation | snGFP |
Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
Target Background | The microtubule-associated protein tau (MAPT)'s transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. |
Target Synonym | TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103; microtubule-associated protein tau; G protein beta1/gamma2 subunit-interacting factor 1; PHF-tau; microtubule-associated protein tau, isoform 4; neurofibrillary tangle protein; paired helical filament-tau; protein phosphatase 1, regulatory subunit 103 |
Gene ID | 4137 |
UniProt ID | P10636 |
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