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Research-Grade Bacteria Production Services

In the ever-evolving landscape of microbiological research, the demand for high-quality bacterial production services has grown exponentially. Researchers and institutions require reliable and efficient solutions for strain production, plasmid generation, primer/probe design, synthesis, bacterial sequencing, and analysis. Creative Biolabs can provide comprehensive research-grade bacterial production services to advance bacterial infection drug discovery.

Strain Production Service

Research-grade bacterial production services begin with the cultivation and production of specific bacterial strains tailored to the unique needs of researchers. These services encompass the isolation, culture, and scale-up of strains, ensuring purity, viability, and genetic stability. Advanced techniques, such as fermentation and bioprocess optimization, are employed to meet varying production scales, from laboratory-scale experiments to industrial applications.

Strain Plasmid Production Service

Plasmids are essential genetic tools in bacterial research, enabling the introduction and expression of specific genes. Research-grade bacterial production services include the generation of high-quality plasmids compatible with various bacterial strains. This involves plasmid design, construction, amplification, and purification to deliver reliable genetic material for experimental manipulation.

Primer/Probe Design and Synthesis Service for Specific Strains

Accurate and specific primer/probe design is crucial for successful molecular biology experiments, particularly in PCR and qPCR assays. Bacterial production services extend their support by offering custom primer and probe design services tailored to specific strains. High-quality synthesis methods ensure the production of primers and probes with precise sequences, melting temperatures, and minimal cross-reactivity, enhancing the reliability of downstream applications.

Bacterial Sequencing and Analysis Service

  • Advancements in genomics have underscored the importance of bacterial sequencing for understanding microbial diversity, evolution, and functional genomics. Bacterial production services include comprehensive sequencing solutions, employing state-of-the-art technologies such as next-generation sequencing (NGS). This facilitates whole-genome sequencing, metagenomics, and transcriptomics, allowing researchers to unravel the intricacies of bacterial genomes.
  • Beyond sequencing, research-grade bacterial production services also offer sophisticated analytical tools for interpreting genomic data. Bioinformatics analysis, comparative genomics, and pathway analysis contribute to a deeper understanding of bacterial physiology, virulence, and adaptation mechanisms. These services are critical for getting relevant insights from the massive amounts of genetic data obtained through sequencing.

Fig. 1 Potential optimization flow for bacterial scale production. (Wehrs, et al., 2019)Fig. 1 Potential optimization flow for bacterial scale production.1

Research-grade bacterial production services are the backbone of bacterial drug discovery research. Creative Biolabs offers a complete line of solutions for strain production, plasmid generation, primer/probe design, synthesis, sequencing and analysis. These services empower researchers to focus on scientific research while ensuring the reliability, reproducibility and efficiency of the experiments. Please contact us to learn more.

Reference:

  1. Wehrs, Maren, et al. "Engineering robust production microbes for large-scale cultivation." Trends in microbiology 27.6 (2019): 524-537.
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