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Non-Pharmaceutical Grade Drug Discovery Services for Bacteria Infection Research

Creative Biolabs specializes in providing non-pharmaceutical grade drug discovery services for a wide range of bacterial infections to help clients conduct effective anti-bacterial drug research. We carry out high-quality experimental design and testing using leading-edge screening techniques and equipment to screen and characterize compounds with anti-bacterial activity from both natural and synthetic sources.

Discovery Strategies for Antibacterial Drugs

  • Natural product discovery.

Screening and identification of antibacterial chemicals derived from natural resources. These natural products may be derived from plants, animals, microbes, and other species with various chemical structures and distinct biological activity. New antibacterial medications can be found by extensive investigation and optimization of these molecules.

  • Research on bacterial drug resistance.

Through genomic and proteomic studies of drug-resistant bacteria, new therapeutic targets can be identified, providing clues for the development of new antibacterial drugs.

  • Research and development of immunomodulators.

Immunomodulators can enhance the ability to fight infections by modulating the immune system. These drugs can be used as adjuvant therapy to boost the effectiveness of other antimicrobials or as prophylaxis to lessen the risk of infection.

  • Development of combination drugs.

Combination drugs are a new paradigm of drug therapy that can increase antimicrobial efficacy and reduce the development of drug resistance through the simultaneous use of two or more drugs. This strategy allows for the development of more effective antimicrobial drugs for a wide range of bacteria and infections.

  • Immunotherapy for infection control.

Immunotherapy is a method of treating infections by boosting the immune system. Through vaccination and immunoglobulin therapy, the body's ability to fight infection can be enhanced to prevent and treat bacterial infections.

Fig. 1 Overview of multiple preclinical antimicrobial drug types. (Theuretzbacher, et al., 2020)Fig. 1 Overview of multiple preclinical antimicrobial drug types.1

Non-Pharmaceutical Grade Drug Discovery Services for Bacteria Infection Research

We utilize the unique role of phages against drug-resistant bacteria to discover and identify new phages with the potential to combat drug-resistant bacterial strains, as well as to support the modification of phages to provide solutions for clients conducting research to overcome antibiotic resistance challenges.

Our hit characterization services identify and develop drug candidates with potential antimicrobial activity through pathogen identification, drug susceptibility testing, biofilm testing, immunological studies and genomic assays. We characterize the antibacterial effects and mechanisms of these drug candidates using a variety of biochemical, cellular and structural biology techniques to gain insights into drug-target interactions and provide the basis for the development of more effective antibacterial medications.

Our services also expand the scope of antimicrobial drug discovery by targeting diverse common bacterial infections. Through diverse screening strategies and technologies, we identify and characterize drug candidates exhibiting resistance to common bacteria, providing more effective therapeutic options for subsequent clinical studies and accelerating drug development.

We also provide research-grade bacterial production services, delivering researchers with high-quality, standardized bacterial products and validation services to ensure that clients' experimental materials are guaranteed to the greatest extent possible, assisting in the achievement of reliable results in bacterial infection research.

Creative Biolabs keeps respect for scientific research and clients' demands in mind and is committed to providing reliable drug discovery services for anti-bacterial infection research. Please contact our professional team for a satisfactory solution.

Reference:

  1. Theuretzbacher, Ursula, et al. "The global preclinical antibacterial pipeline." Nature Reviews Microbiology 18.5 (2020): 275-285.
For Research Use Only. We do not provide direct services or products for patients.
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