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Non-Pharmaceutical Grade Drug Discovery Services for Virus Infection Research

Creative Biolabs provides comprehensive antiviral drug discovery and testing services, covering the entire process from hits screening to drug production. Our team has extensive drug discovery experience and an in-depth understanding of virology, providing reliable solutions to assist clients in antiviral drug discovery.

Antiviral Drug Discovery Strategies

  • Viral target screening and validation. Sequencing and analyzing the viral genome through bioinformatics and molecular biology techniques to identify possible drug targets and validate their effectiveness.
  • Drug design and optimization. Design and screen potential therapeutic compounds based on the structure and function of viral targets, and then test their activity and selectivity in trials.
  • Drug synthesis and preparation. Synthesize and prepare the screened drug molecules for subsequent efficacy and safety evaluation.
  • Efficacy and safety assessment. In vitro and in vivo assays are performed to evaluate the efficacy and safety of the drug, including antiviral activity, cytotoxicity, drug metabolism, drug distribution, and drug elimination. Then it is possible to advance the drug molecule to the next stage of trials.

Non-Pharmaceutical Grade Drug Discovery Services for Virus Infection Research

We are capable of hit characterization to assess the efficacy and toxicity of possible non-pharmaceutical grade pharmaceuticals against anti-DNA or anti-RNA viruses. Observations and evaluations are conducted using high-throughput screening techniques to accurately predict the performance of non-pharmaceutical-grade drugs in trials and to delve into the mechanisms underlying the pharmacological effects of antiviral drugs and their interactions with viruses in the host. We carry out this work using the most rigorous biochemistry, molecular biology and cell biology techniques and methods.

The common subtypes of viruses that trigger infections are classified by nucleic acid type into DNA and RNA types, and can be further subdivided into double-stranded, single-stranded, and retroviruses. Our non-pharmaceutical grade drug development services include infection investigations with several common viral subtypes. Our team offers extensive expertise and technological capabilities ranging from the identification of viral targets to the screening and optimization of therapeutic candidates.

Our research-grade virus technical services are focused on the design, synthesis and production of a broad group of viruses, including pseudoviruses, virus-like particles and recombinant viral proteins, for drug screening and research. In the meantime, powerful sequencing and analysis tools ensure that viruses are delivered with a high degree of reliability and validity.

Fig. 1 A route for virtual screening of antiviral products against viral proteins. (Adamson, et al., 2021)Fig. 1 A route for virtual screening of antiviral products against viral proteins.1

Strengths of Drug Discovery Services for Viral Infection Research

  • Targeting viral characteristics. Design drug discovery programs based on virus characteristics and replication processes to achieve more effective drug results.
  • Efficient. Modern drug design and screening methods, such as high-throughput screening and computer-aided drug design, can significantly increase drug discovery efficiency and accuracy.
  • Specificity. Discover more specific and targeted non-pharmaceutical grade drugs for specific virus species.
  • Drug resistance avoidance. Consider avoiding the risk of drug resistance in the drug discovery strategy to ensure the sustainability of the drug's effects.
  • Extensive. Non-pharmaceutical drugs with broad spectrum can also be discovered for a multitude of viral diseases.

Creative Biolabs is dedicated to providing non-pharmaceutical grade active compound screening and viral inhibitor drug discovery services to help clients better study and understand the mechanisms of different viral infections. We provide efficient, rapid, and customized solutions to support your research and drug discovery goals. Please contact us for further information.

Reference:

  1. Adamson, Catherine S., et al. "Antiviral drug discovery: preparing for the next pandemic." Chemical Society Reviews 50.6 (2021): 3647-3655.
For Research Use Only. We do not provide direct services or products for patients.
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For Research Use Only. We do not provide direct services or products for patients.

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