Bromodomain-containing Protein 4 (CAT#: PRLP-001)
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Datasheets
| Protein Information |
|---|
| Protein Name |
Bromodomain-containing Protein 4 |
| Alternative Names |
CDLS6; FSHRG4; BRD4; CAP; HUNK1; HUNKI; MCAP; Bromodomain Containing 4 |
| Gene Name |
BRD4 |
| Species |
Human |
| Introduction |
BRD4 is a member of the BET (bromodomain and extra terminal domain) family. It has two bromodomains BD1 and BD2. BRD4 is a major target of BET inhibitors, a class of pharmaceutical drugs currently being evaluated in clinical trials. |
| Function |
BRD4 is often required for expression of Myc and other "tumor driving" oncogenes in hematologic cancers including multiple myeloma, acute myelogenous leukemia, and acute lymphoblastic leukaemia. |
| Related Disease |
NUT midline carcinoma |
| Gene ID |
23476 |
| UniProt ID |
O60885 |
| Product Specifications |
|---|
| Expression System |
E. coli |
| Expression Length(a.a) |
49-460 |
| Molecular Weight (kDa) |
46.9 |
| Tags |
None |
| Purity |
90% |
| Size |
0.1 mg |
| Physical State |
Aqueous buffer solution |
| Storage |
Stored at -80°C. Avoid freeze/thaw cycles. |
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