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Datasheets
| Protein Information | |
|---|---|
| Protein Name | Bromodomain-containing Protein 4 |
| Alternative Names | CDLS6; FSHRG4; BRD4; CAP; HUNK1; HUNKI; MCAP; Bromodomain Containing 4 |
| Gene Name | BRD4 |
| Species | Human |
| Introduction | BRD4 is a member of the BET (bromodomain and extra terminal domain) family. It has two bromodomains BD1 and BD2. BRD4 is a major target of BET inhibitors, a class of pharmaceutical drugs currently being evaluated in clinical trials. |
| Function | BRD4 is often required for expression of Myc and other "tumor driving" oncogenes in hematologic cancers including multiple myeloma, acute myelogenous leukemia, and acute lymphoblastic leukaemia. |
| Related Disease | NUT midline carcinoma |
| Gene ID | 23476 |
| UniProt ID | O60885 |
| Product Specifications | |
|---|---|
| Expression System | E. coli |
| Expression Length(a.a) | 49-460 |
| Molecular Weight (kDa) | 46.9 |
| Tags | None |
| Purity | 90% |
| Size | 0.1 mg |
| Physical State | Aqueous buffer solution |
| Storage | Stored at -80°C. Avoid freeze/thaw cycles. |
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