Please feel free to contact us for a quote and further discussion with our scientists.
Datasheets
| Protein Information | |
|---|---|
| Protein Name | Recombinant Human XIAP protein, Fc Tag |
| Alternative Names | API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3 |
| Gene Name | XIAP |
| Species | Human |
| Introduction | X-linked inhibitor of apoptosis protein (XIAP) is a multi-domain E3 ligase containing three baculoviral IAP repeats (BIRs) and a C-terminal RING finger domain. It directly binds caspases through BIR domains. |
| Function | XIAP (X-linked Inhibitor of Apoptosis) is a multi-functional RING-type E3 ligase containing BIR domains. When harnessed for targeted destruction, XIAP provides an attractive alternative to traditional ligases, utilizing its specific BIR-binding chemical handles to establish stable ternary architectures and trigger the degradation of refractory oncogenic drivers. |
| Related Disease | Various cancers (overexpression confers chemoresistance and poor prognosis) |
| Gene ID | 331 |
| UniProt ID | P98170 |
| Product Specifications | |
|---|---|
| Expression System | E. coli |
| Expression Length(a.a) | 497 |
| Molecular Weight (kDa) | 57 |
| Purity | 0.9 |
| Size | 0.1 mg |
| Physical State | Aqueous buffer solution |
| Storage | Stored at -80 °C. Avoid freeze/thaw cycles. |
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
