Recombinant Human XIAP protein, Fc Tag (CAT#: PRLP-006)
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Datasheets
| Protein Information |
|---|
| Protein Name |
Recombinant Human XIAP protein, Fc Tag |
| Alternative Names |
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3 |
| Gene Name |
XIAP |
| Species |
Human |
| Introduction |
X-linked inhibitor of apoptosis protein (XIAP) is a multi-domain E3 ligase containing three baculoviral IAP repeats (BIRs) and a C-terminal RING finger domain. It directly binds caspases through BIR domains. |
| Function |
XIAP (X-linked Inhibitor of Apoptosis) is a multi-functional RING-type E3 ligase containing BIR domains. When harnessed for targeted destruction, XIAP provides an attractive alternative to traditional ligases, utilizing its specific BIR-binding chemical handles to establish stable ternary architectures and trigger the degradation of refractory oncogenic drivers. |
| Related Disease |
Various cancers (overexpression confers chemoresistance and poor prognosis) |
| Gene ID |
331 |
| UniProt ID |
P98170 |
| Product Specifications |
|---|
| Expression System |
E. coli |
| Expression Length(a.a) |
497 |
| Molecular Weight (kDa) |
57 |
| Purity |
0.9 |
| Size |
0.1 mg |
| Physical State |
Aqueous buffer solution |
| Storage |
Stored at -80 °C. Avoid freeze/thaw cycles. |
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