Super™ Llama Anti-ARTC2 Single Domain Antibody-sn-mNeptune (S+16a)(Cat#: MDWJ2251)
This product is a Llama single domain antibody recognizes ARTC2 conjugated to sn-mNeptune. This product has the ability for cell penetration.
Datasheets| Target | ARTC2 |
| Immunogen | Expression vector encoding full length mouse ARTC2. |
| Species Reactivity | Mouse |
| Application | BL, Cell Penetration |
| Clone | S+16a |
| Host Animal | Llama |
| Isotype | sdAb |
| Clonality | Monoclonal |
| Class | Primary |
| Concentration | 1 mg/mL |
| Conjugation | sn-mNeptune |
| Storage Condition | Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles. |
| Target Background | ARTC2, also known as ART2.2, is a 35 kD, GPI-anchored, and cell surface ADP-ribosyltransferase that is highly expressed by regulatory T cells (Tregs) and natural killer T (NKT) cells. ARTC2 is enzymatically active at 4°C. Through the ribosylation of the ion channel P2X7, ARTC2 mediates NAD+-induced cell death (NICD) and the proteolytic shedding of CD27 and CD62L. Blocking the activity ARTC2 with Treg-Protector improves the recovery of Tregs and NKT cells during their isolation from lymphatic and peripheral tissues. |
| Target Synonym | Art Rt6; Rt-6; ARTC2; Ly92b; Rt6-2; ART2. 2; Art2b; ADP-ribosyltransferase 2b |
| Gene ID | 7011691 |
| UniProt ID | O35975 |
See other products for " ARTC2 "
KINDLY NOTE
- Some properties of custom products can be tailored flexibly. Please feel free to send your specific demands through an inquiry.
- All listed customized sdAb products are for lab research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use. For commercial purpose, please review our one-stop solutions for de novo sdAb discovery.
- No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
- NCBI/UniProt data is used to refer general target information. It may not necessarily be applicable to one specific product.
- Creative Biolabs has made every effort to ensure the accuracy of the datasheet and reserves the right to make changes to the datasheet at any time without prior notice. Creative Biolabs will not be liable for any omissions or errors contained herein, please use the COA of your custom products as standard.
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For Research Use Only. Not for diagnostic or therapeutic applications.
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