AF488-labeled Human CA9 (38-414) CAR Detection Reagent, His Tag (XS-1223-LX19)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Specifications

Target
CA9

Organism
Human

Application
Used for evaluating CAR expression.

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
This product is recommended for FC application, and the optimal working dilutions should be determined by the end user.

Diseases
Renal cell carcinoma

Molecular Characterization
The CAR detection reagent contains AA Gln 38 - Asp 414 of Human CA9.

Conjugation
AF488

Size
25µg; 100µg

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

Target Alternative Names
carbonic anhydrase 9

Entrez Gene ID
768

UniProt ID
P40259-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

AF488-labeled Human CA9 (38-414) CAR Detection Reagent, His Tag (XS-1223-LX19)

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Specifications

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