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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Creative Biolabs offers a wide range of HMMR CAR vector products, CAR cell products, CAR animal cells, and CAR mRNA products to advance your R&D journey. You can search below to select the product you need.
Studies have shown that hyaluronan-mediated motility receptor (HMMR) can interact with BRCA1 and further regulate cell division and parietal and bastard polarization of breast epithelial cells, so HMMR is considered a potential regulator of BRCA1-related breast cancer risk. However, the molecular and cellular changes produced by risk regulators are not well understood, and their impact on disease subtypes and disease occurrence and progression is unclear.
Fig.1 Strategies to improve androgen receptor signaling inhibitors response by targeting HMMR.1
Colorectal Cancer
Hepatocellular Carcinoma
We have mature platforms and systems for molecular cloning, lentivirus, retroviral packaging, HMMR CAR-T cell preparation. In the one-stop CAR-T therapy development platform, we provide scientific research services such as biomarker identification and selection, and high-affinity scFv generation.
Creative Biolabs has an advanced technology platform and a professional R&D team that is responsible for the custom design and construction services of HMMR CAR. We offer a wide range of classic CAR constructions with different structural modifications. In addition, Creative Biolabs also offers designs for special CARs, such as TanCAR Construction.
Creative Biolabs offers custom services for engineered cell lines, such as labeling target cells with luciferase and GFP genes, as well as custom construction services for gene stabilization, overexpression, and knockdown of target cells.
Creative Biolabs provides a full range of in vitro functional testing services for transfected anti-HMMR CAR-T cells, including but not limited to CAR expression testing, cytokine release test, in vitro toxicity assessment, and in vitro pharmacodynamic analysis. You can click on the link above to get more in vitro testing services for anti-HMMR CAR-T cells.
In addition, Creative Biolabs offers a variety of in vivo CAR-T assays to create a comprehensive preclinical integrated customized solution for in vivo efficacy studies, toxicity assessment, viability assays, and quality control of your anti-HMMR CAR-T cells through suitable animal models.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-1122-YF515 | Anti-HMMR KIR CAR (scFv-KIR2DS2-DAP12, XW-515), pCDCAR1 | Human | XW-515 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF516 | Anti-HMMR KIR CAR (scFv-KIR2DS2-DAP12, XW-516), pCDCAR1 | Human | XW-516 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF517 | Anti-HMMR KIR CAR (scFv-KIR2DS2-DAP12, XW-517), pCDCAR1 | Human | XW-517 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF518 | Anti-HMMR KIR CAR (scFv-KIR2DS2-DAP12, XW-518), pCDCAR1 | Mouse | XW-518 | Rat | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF1435 | Anti-HMMR TCR-ABR (scFv-TCRα, XW-515) CAR Plasmid, pCDCAR1 | Human | XW-515 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1436 | Anti-HMMR TCR-ABR (scFv-TCRα, XW-516) CAR Plasmid, pCDCAR1 | Human | XW-516 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1437 | Anti-HMMR TCR-ABR (scFv-TCRα, XW-517) CAR Plasmid, pCDCAR1 | Human | XW-517 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1438 | Anti-HMMR TCR-ABR (scFv-TCRα, XW-518) CAR Plasmid, pCDCAR1 | Mouse | XW-518 | Rat | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF2355 | Anti-HMMR TCR-ABR (scFv-TCRβ, XW-515) CAR Plasmid, pCDCAR1 | Human | XW-515 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF2356 | Anti-HMMR TCR-ABR (scFv-TCRβ, XW-516) CAR Plasmid, pCDCAR1 | Human | XW-516 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF2357 | Anti-HMMR TCR-ABR (scFv-TCRβ, XW-517) CAR Plasmid, pCDCAR1 | Human | XW-517 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF2358 | Anti-HMMR TCR-ABR (scFv-TCRβ, XW-518) CAR Plasmid, pCDCAR1 | Mouse | XW-518 | Rat | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF3275 | Anti-HMMR TCR-ABR (scFv-CD3γ, XW-515) CAR Plasmid, pCDCAR1 | Human | XW-515 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3276 | Anti-HMMR TCR-ABR (scFv-CD3γ, XW-516) CAR Plasmid, pCDCAR1 | Human | XW-516 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3277 | Anti-HMMR TCR-ABR (scFv-CD3γ, XW-517) CAR Plasmid, pCDCAR1 | Human | XW-517 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3278 | Anti-HMMR TCR-ABR (scFv-CD3γ, XW-518) CAR Plasmid, pCDCAR1 | Mouse | XW-518 | Rat | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF4195 | Anti-HMMR TCR-ABR (scFv-CD3δ, XW-515) CAR Plasmid, pCDCAR1 | Human | XW-515 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4196 | Anti-HMMR TCR-ABR (scFv-CD3δ, XW-516) CAR Plasmid, pCDCAR1 | Human | XW-516 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4197 | Anti-HMMR TCR-ABR (scFv-CD3δ, XW-517) CAR Plasmid, pCDCAR1 | Human | XW-517 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4198 | Anti-HMMR TCR-ABR (scFv-CD3δ, XW-518) CAR Plasmid, pCDCAR1 | Mouse | XW-518 | Rat | scFv-CD3δ | Lentiviral vector | T Cell |
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