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This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-0822-YF635 | Anti-Human MAGE-A4 (XW-635) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-635 | Mouse | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF636 | Anti-Mouse MAGE-A4 (XW-636) m(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-636 | Rat | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1555 | Anti-Human MAGE-A4 (XW-635) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-635 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1556 | Anti-Mouse MAGE-A4 (XW-636) m(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Mouse | XW-636 | Rat | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-1122-YF3395 | Anti-MAGE-A4 TCR-ABR (scFv-CD3γ, XW-635) CAR Plasmid, pCDCAR1 | Human | XW-635 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3396 | Anti-MAGE-A4 TCR-ABR (scFv-CD3γ, XW-636) CAR Plasmid, pCDCAR1 | Mouse | XW-636 | Rat | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF4315 | Anti-MAGE-A4 TCR-ABR (scFv-CD3δ, XW-635) CAR Plasmid, pCDCAR1 | Human | XW-635 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4316 | Anti-MAGE-A4 TCR-ABR (scFv-CD3δ, XW-636) CAR Plasmid, pCDCAR1 | Mouse | XW-636 | Rat | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF5235 | Anti-MAGE-A4 TCR-ABR (scFv-CD3ε, XW-635) CAR Plasmid, pCDCAR1 | Human | XW-635 | Mouse | scFv-CD3ε | Lentiviral vector | T Cell | ||
| XS-1122-YF5236 | Anti-MAGE-A4 TCR-ABR (scFv-CD3ε, XW-636) CAR Plasmid, pCDCAR1 | Mouse | XW-636 | Rat | scFv-CD3ε | Lentiviral vector | T Cell | ||
| XS-1122-YF6155 | Anti-MAGE-A4 (XW-635) h(CD28-CD3ζ) CAR, pAAV | Human | XW-635 | Mouse | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF6156 | Anti-MAGE-A4 (XW-636) h(CD28-CD3ζ) CAR, pAAV | Mouse | XW-636 | Rat | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF7075 | Anti-MAGE-A4 (XW-635) h(41BB-CD3ζ) CAR, pAAV | Human | XW-635 | Mouse | scFv-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF7076 | Anti-MAGE-A4 (XW-636) h(41BB-CD3ζ) CAR, pAAV | Mouse | XW-636 | Rat | scFv-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF7995 | Anti-MAGE-A4 (XW-635) h(CD28-41BB-CD3ζ) CAR, pAAV | Human | XW-635 | Mouse | scFv-CD28-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-1122-YF7996 | Anti-MAGE-A4 (XW-636) h(CD28-41BB-CD3ζ) CAR, pAAV | Mouse | XW-636 | Rat | scFv-CD28-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-0123-ZP311 | Anti-MAGE-A4 (CB-P35) h(scFv-CD3ε) TRuC, pCDTRC1 | Human | CB-P35 | Mouse | scFv-CD3ε | Lentiviral vector | T cell | ||
| XS-0123-ZP549 | Anti-MAGE-A4 (CB-P34) h(scFv-CD3ε) TRuC, pCDTRC1 | Mouse | CB-P34 | Rat | scFv-CD3ε | Lentiviral vector | T cell | ||
| XS-0323-ZP311 | Anti-MAGE-A4 (CB-P35 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | CB-P35 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP549 | Anti-MAGE-A4 (CB-P34 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Mouse | CB-P34 | Rat | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector |
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CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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